Treatment of Attention Deficit Hyperactivity Disorder (ADHD) with Strattera®

2019-10-07

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The Centers for Disease Control says that as many as 11% of children in the United States age 4-17 years of age have been diagnosed with ADHD. The number of diagnosed cases in adults is approximately 4.4%.

What is ADHD? According to the National Institute of Mental Health (NIH) attention deficit hyperactivity disorder (ADHD) is “a brain disorder marked by an ongoing pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or development.

ADHD is a legitimate diagnosis and has been recognized by:

U.S. Department of Education

American Psychiatric Association

National Institutes of Health

Symptoms of ADHD can appear as early as 3-6years of age and can unfortunately be mistaken as simple bad behavior due to poor parenting skills. It is important to note that people with ADHD do not have it because they are less intelligent, are “behaving badly” or are defiant.

The definition:

Attention deficit – this is the inattention to details and trouble keeping focus, disorganization, and sometimes wandering off. This is not related to lack of understanding, comprehension or bad attitude.

Hyperactivity – this is the constant need to move, such as fidgeting, tapping, talking, and restlessness. With this comes impulsivity – making decisions and/or taking actions without thinking of the long term effects, possible harm or outcome. There is a need for immediate gratification and action.

There are treatments that can and often do help reduce symptoms and improve day to day functions, but at this time there is no cure. Often a combination of treatments such as psychotherapy, education, behavior therapy and prescription medication may help patients.

Prescription Strattera ® (atomoxetine) for ADHD treatment

Strattera® (atomoxetine) is a non-stimulant medication used for the treatment of ADHD. It is the first non-stimulant medication approved by the FDA. It works on a particular chemical in the brain that transmits nerve impulses, known as neurotransmitter, called norepinephrine. By Strattera® increasing the amount of norepinephrine in the brain the patient may see a decrease in hyperactivity and improved impulse behavior as well as an increase in their ability focus and their attention span.

Unlike psychostimulants that are often used as treatment for ADHD, Strattera® does not cause many of the side effects such as sleeplessness. Still, when Strattera® is started there may be side effects such as nausea, drowsiness and abdominal pain when the medication is first started. Because Strattera®is not a controlled substance, there is less chance the patient will become dependent on it or abuse it.

Side effects of Strattera® in adults may include:

Constipation

Dry mouth

Insomnia

Erectile dysfunction

Hot flashes

Painful menstruation

Side effects of Strattera® in adolescents and children may include:

Mood swings

Tiredness

Dizziness

Nausea or upset stomach

Decreased appetite

Abdominal pain

Other side effects and reactions, such as an increase in suicidal thoughts in teens have been reported while first taking Strattera®. Always speak to your pharmacist about potential concerns with this or any other medication you may be taking.

Tell your doctor if you have high blood pressure, heart problems, or a history of heart disease. It is also important to tell your doctor if anyone in your family, including yourself, has ever had suicidal thoughts, low blood pressure, liver disease, depression, mental illness, psychosis or bipolar disorder.

Strattera® Capsules

Strattera® is available in 10mg, 18mg, 25mg, 40mg, 60mg, 80mg and 100mg capsules

Adult dose:

Initial dose: 40mg tablet once a day.

Maintenance dose: 80mg/day after at least 3 days at the initial dose level

Maximum dose: up to 100mg/day after at least 2-4 days at the maintenance dose level.

Pediatric dose

Strattera® is prescribed according to the weight of the child or adolescent taking the medication. The total dose in children and adolescents should not exceed 1.4mg/kg or 100mg, whichever is less.

70kg or less:

Initial dose: 0.5mg/kg/day

Maintenance dose: 1.2mg/kg/day after at least 3 days at the initial dose level.

Maximum dose: 1.4mg/kg/day or 100mg/day, whichever is less.

Over 70kg:

Initial dose: 40mg/day

Maintenance dose: 80mg/day after at least 3 days at the initial dose level.

Maximum dose: 100mg/day, whichever is less.

If Strattera® is to be used for an extended period of time your physician should reevaluate the effectiveness of the medication on a regular basis.

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