2024-07-11
Alprostadil is a prostaglandin analog medication used to treat erectile dysfunction in males and maintain ductus arteriosus patency in newborns with congenital heart diseases before surgery. It works by increasing blood flow to the penis and keeping the ductus arteriosus open.
Below is a table comparing the different alprostadil products:
Product name | Region(s) Available | Formulation | Key Features |
United Kingdom | Dual chamber cartridge in a single use injection device | Easy to use, premeasured doses, sterile | |
New Zealand | Dual chamber cartridge in a single use injection device | Easy to use, premeasured doses, sterile | |
Canada & United Kingdom | Vial with separate syringe injector | Requires mixing of diluent with powder, offers flexibility in dosing but is not as convenient | |
United Kingdom | Reusable injection device with cartridges | Ready to use, sterile
| |
USA | Reusable injection device with cartridges | Ready to use, sterile |
Author: Daniel Valera Property of Jason’s Canada Drugstore
Note: All products are administered through Intracavernosal injection (an injection into the base of the penis).
Product name | Dual chamber cartridge in a single use injection device | Reusable Injector Device | Individual Cartridges for Device | Vial to be used with a syringe |
✅ | ❌ | ❌ | ❌ | |
✅ | ❌ | ❌ | ❌ | |
❌ | ❌ | ❌ | ✅ | |
❌ | ✅ | ✅ | ❌ | |
❌ | ✅ | ✅ | ❌ |
Author: Jason P. Property of Jason’s Canada Drugstore
This table should help consumers compare the different Alprostadil products based on their needs and preferences.
Injectable ED medications have a high success rate in producing erections suitable for sexual intercourse.
These medications typically work within 5 to 20 minutes after injection, providing a quick solution for ED.
Since the medication is injected directly into the penis, it often works more effectively and faster than oral medications.
Injectable medications can be a viable option for men who do not respond well to oral ED treatments.
The dosage can be adjusted to meet individual needs, providing more control over the strength and duration of the erection.
Caverject dual chamber, Caverject Impulse (alprostadil)
Caverject dual chamber and Caverject Impulse (alprostadil) are indicated for the symptomatic treatment of erectile dysfunction in adult males, administered through Intracavernosal injection.
Caverject Dual Chamber and Caverject Impulse are manufactured by Pfizer Inc.
Both are available in 10 mcg and 20 mcg strengths. The alprostadil comes as a sterile, freeze-dried powder for reconstitution in a prefilled, dual chamber glass cartridge. The front chamber contains alprostadil, and the rear chamber contains sterile bacteriostatic water.
Both use the same delivery system. They both use a dual chamber glass cartridge contained in a single-use, disposable injection delivery device.
Caverject Dual Chamber and Caverject Impulse work by relaxing the blood vessels and muscles in the penis, increasing blood flow to help achieve and maintain an erection.
The medication is administered via intracavernosal injection. The dual chamber cartridgecontained in the single use delivery injection device makes it easier to mix and administer the dose.
Common side effects include mild to moderate pain at the injection site, penile pain, and sometimes prolonged erection (priapism).
If you experience an erection lasting more than 4 hours (priapism), seek immediate medical attention to avoid further discomfort.
No, the syringe/injection device and needle are designed for single use only. Dispose of them properly after use.
Caverject vial kit (alprostadil) offers dosing flexibility but requires the user to mix the solution before injection, it includes a vial of alprostadil powder, a diluent (sterile water or bacteriostatic water), and a syringe and needles for mixing and for administration.
Image source: https://labeling.pfizer.com/ImageHandler.ashx?id=19936
Caverject vial kit is manufactured by Pfizer Inc.
Caverject vial kit is available in single dose vials containing 10 mcg or 20 mcg of alprostadil.
Alprostadil, the active ingredient, works by relaxing blood vessels and muscles in the penis, increasing blood flow to help achieve and maintain an erection.
Reconstitute the alprostadil powder by mixing it with the provided sterile water or bacteriostatic water. Draw up the solution at the appropriate dose into the syringe for injection.
Same with the Caverject impulse and dual chamber. No, the syringe and needle are designed for single use only. Dispose of them properly after use.
Viridal Duo Starter Pack (alprostadil) is another treatment for erectile dysfunction that includes individual cartridges with two chambers containing alprostadil and the diluent (sterile saline), a reusable injector device, and other necessary components for administration.
Viridal Duo starter pack is manufactured by Advanz Pharma.
Viridal Duo starter pack is available in 10 mcg, 20 mcg, and 40 mcg.
Common side effects include mild to moderate pain at the injection site, penile pain, and sometimes prolonged erection (priapism).
The injector device in the Viridal Duo Starter Pack is typically designed for multiple uses, but needles and cartridges should not be reused.
The medication typically takes effect within 5 to 20 minutes after injection, though this can vary between individuals.
The effect of the medication usually lasts for about 1 hour, but this can vary depending on the individual.
Edex is a sterile, pyrogen free powder containing alprostadil, which is another treatment for erectile dysfunction that is easy to use and comes in dual chamber cartridges with a reusable injection device.
Edex is manufactured by Endo Pharmaceuticals.
The Edex (alprostadil) cartridges are supplied in three strengths: 10 mcg, 20 mcg and 40 mcg How long does it take for Edex to start working?
Edex typically starts working within 5 to 20 minutes after injection, and the effects can last for up to one hour.
Edex should not be used more than three times a week, with at least 24 hours between doses.
Edex may interact with certain medications, including blood thinners and medications for high blood pressure.
Edex may not be suitable for all men, especially those with certain medical conditions or risk factors.
You should not use Edex in combination with other ED treatments unless advised by your healthcare provider. Mixing treatments can increase the risk of side effects.
Yes, there are several alternatives, including oral medications (like Viagra, Cialis), vacuum erection devices, and penile implants.
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