Abiraterone acetate (Zytiga) works by reducing male hormone (androgen) production in the body – hormones like testosterone, that can promote tumor growth in the prostate gland.
Generic version of Zytiga have been launched by Apotex, Pharmascience, Hikma, Mylan, Teva and Indian pharmaceutical company, Cipla.
What is Zytiga?
Zytiga is a brand-name prescription medication that contains abiraterone acetate. The Janssen Pharmaceutical Companies of Johnson & Johnson launched Zytiga in 2011.
Abiraterone is not a form of chemotherapy. It is a hormone therapy medication.
What Is Zytiga Used For?
It is approved by the U.S Food and Drug Administration (FDA) to treat two types of prostate cancer:
Metastatic means the cancer has spread to other parts of the body. Both above cancers are considered advanced.
Although Zytiga is not FDA-approved to treat non-metastatic prostate cancer, the American Urological Association recommends Zytiga as an option for patients.
According to findings from the study, Zytiga in combination with low-dose prednisone also significantly lowered PSA levels with a consistent toxicity profile in men with high-risk non-metastatic castration-resistant prostate cancer (CRPC).
Why Does Abiraterone Need to Be Given with Prednisone?
You take abiraterone with a steroid called prednisone to help reduce some of the side effects, such as low potassium or high blood pressure.
What Are the Possible Side Effects of Abiraterone Acetate (Zytiga)？
The most common side effects of abiraterone acetate include:
Abiraterone acetate may cause fertility problems in males, which may affect the ability to father children. Talk to your healthcare provider if you have concerns about fertility.
How Much Can You Save From Canadian Online Mail-Order Pharmacies?
The average retail price for the brand Zytiga (250 mg) is around $100 per tab in the United States (source from goodrx.com), while the brand Zytiga manufactured by same company Janssen is only $36.88 per tab from Canadian pharmacies.
Xbira is the generic abiraterone acetate manufactured by Cipla from India. The price is only $6.79 per tab (250 mg).
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