Tell your doctor if you have ever had or may be:
- antiphospholipid syndrome (autoimmune disorder);
- kidney disease (or if you are on dialysis);
- liver disease; or
- pregnant or planning to become pregnant.
Apixaban may cause you to bleed more easily, especially if you have a bleeding disorder that is inherited or caused by disease.
Special consideration will be observed if you:
- are older than 80; or
- weigh less than 132 pounds.
Apixaban can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if:
- a spinal catheter in place or if a catheter has been recently removed;
- a history of spinal surgery or repeated spinal taps;
- a spinal tap or epidural anesthesia;
- taking an NSAID (nonsteroidal anti-inflammatory drug)–ibuprofen (Advil, Motrin), naproxen (Aleve), diclofenac, indomethacin, meloxicam, and others; or
- using other medicines to treat or prevent blood clots